Upstate South Carolina Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
Photo by RVLuckyorWhat
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Upstate South Carolina Vacation
With a Upstate South Carolina vacation package, you can forget about the stress of planning and simply focus on experiencing what this thrilling destination has on offer. With so much to do and see on a trip to Upstate South Carolina, it can be hard to know where to begin. Kick off your travels in Greenville at Falls Park on the Reedy and Bon Secours Wellness Arena — two popular attractions here. Another top city worthy of a spot on your itinerary is Spartanburg. Don't miss WestGate Mall and Tyger River Park. Expedia is your one-stop shop for planning your Upstate South Carolina vacation. From hotels and flights, to car rentals and more, we're here to help you create a travel experience like no other.
Top Upstate South Carolina Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Grand Bohemian Lodge Asheville, Autograph Collection®
Biltmore Village
Price was CA $2,762, price is now CA $2,311 per person
CA $2,311
per person
Dec 19 - Dec 23
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Asheville (AVL)
9.2/10 Wonderful! (964 reviews)
This hotel was so magical!
Reviewed on Nov 9, 2026
Kimpton Hotel Arras by IHG
Downtown Asheville
Price was CA $1,724, price is now CA $1,488 per person
CA $1,488
per person
Dec 11 - Dec 13
found 16 hours ago
Roundtrip non-stop flight included
Montreal (YUL) to Asheville (AVL)
9.6/10 Exceptional! (1,197 reviews)
Great location, friendly staff and easy onsite valet parking. Would definitely stay here again!
Reviewed on Nov 9, 2026
The Foundry Hotel Asheville, Curio Collection by Hilton
Downtown Asheville
Price was CA $2,034, price is now CA $1,817 per person
CA $1,817
per person
Dec 19 - Dec 23
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Asheville (AVL)
9.4/10 Exceptional! (555 reviews)
The property is immaculate. The housekeeping was excellent. Staff super helpful and this hotel is in a GREAT location. Highly recommend it!
Reviewed on Nov 7, 2026
Where to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
3 out of top 10 points of interest in this area
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Upstate South Carolina Hotel Deals
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $106 per night from Dec 6 to Dec 7
CA $106
CA $117 total
Dec 6 - Dec 7
includes taxes & fees
9.2/10 Wonderful! (1,617 reviews)
"The room was clean however the noises from the outside were very annoying the ice machine was rumbling half the night. I think the room could have provided more soap and other accessories for the bathroom . Overall it was a 9 experience 👍👍"
Reviewed on Nov 9, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
The price is CA $137 per night from Dec 10 to Dec 11
CA $137
CA $155 total
Dec 10 - Dec 11
includes taxes & fees
Days Inn by Wyndham Greenville
60 Roper Mountain Rd Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $88 per night from Nov 29 to Nov 30
CA $88
CA $96 total
Nov 29 - Nov 30
includes taxes & fees
5.6/10 (1,001 reviews)
"Always a great stay"
Reviewed on Nov 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Upstate South Carolina attractions
What to do in Upstate South Carolina
Greenville Ghost Tour with Paranormal Investigation
CA $49
per adult
Frequently asked questions
Explore a world of travel with Expedia
- Residence Inn by Marriott Spartanburg
- Simpsonville Hotels
- Sleep Inn Spartanburg Southwest
- Value Place Hotels in Duncan
- All Inclusive Resorts and in Spartanburg
- Tru by Hilton Spartanburg
- Lyman Hotels
- Cottages in Spartanburg
- Fairfield by Marriott Inn & Suites Spartanburg Downtown
- Holiday Inn Express & Suites Greenville
- Rv Parks in Spartanburg
- Roebuck Hotels
- Crossland Economy Studios Hotels in Spartanburg
- Woodruff Hotels
- Condo Rentals in Spartanburg
- Una Hotels
- Guest Houses in Fountain Inn
- Fountain Inn Hotels
- Motel 6 Hotels in Duncan
- Spartanburg Hotels
- B&B in Pauline
- Hotels with Waterslides in Spartanburg
- Echo Suites Extended Stay by Wyndham Spartanburg
- Five Forks Hotels
- Luxury Hotels in Spartanburg
- Motels in Duncan
- Hotels with an Indoor Pool in Duncan
- Red Roof Inn Hotels in Pauline
- Cheap Hotels in Spartanburg
- Flights from Sudbury (YSB) to Greenville (GSP)
- Flights to Spartanburg
- Flights from London (YXU) to Greenville (GSP)
- Flights from Dallas (DFW) to Greenville (GSP)
- Flights from Kelowna (YLW) to Greenville (GSP)
- Flights from Atlanta (ATL) to Greenville (GSP)
- Flights from Tampa (TPA) to Spartanburg (SPA)
- Flights from Vancouver (YVR) to Spartanburg (SPA)
- Flights from Ottawa (YOW) to Greenville (GSP)
- Flights from Toronto (YYZ) to Greenville (GSP)
- Flights from Spartanburg
- Flights from Manchester (MHT) to Greenville (GSP)
- Flights from Plattsburgh (PBG) to Greenville (GSP)
- Flights to Roebuck
- Flights from Regina (YQR) to Greenville (GSP)
- Flights from Pauline
- Flights from Saskatoon (YXE) to Greenville (GSP)
- Flights from Brandon (YBR) to Greenville (GSP)
- Flights from Raleigh (RDU) to Greenville (GSP)
- Flights to Duncan
- Flights from Edmonton (YEG) to Greenville (GSP)
- Flights to Greenville - Spartanburg
- Flights from Halifax (YHZ) to Greenville (GSP)
- Flights from Charleston (CHS) to Greenville (GSP)
- Flights from Phoenix (PHX) to Greenville (GSP)
- Flights from Greenville-Spartanburg Intl.
- Flights from Seattle (SEA) to Greenville (GSP)
- Flights from Winnipeg (YWG) to Greenville (GSP)
- Flights from Detroit (DTW) to Greenville (GSP)
- Flights from Buffalo (BUF) to Greenville (GSP)
- Flights to Simpsonville
- Flights from Toronto (YYZ) to Spartanburg (SPA)
- Flights from Bangor (BGR) to Greenville (GSP)
- Flights from Watertown (ART) to Greenville (GSP)
- Flights from Oakland (OAK) to Spartanburg (SPA)
- Flights from Moore
- Flights from Bradford (BFD) to Spartanburg (SPA)
- Flights from North Myrtle Beach (CRE) to Spartanburg (SPA)
- Flights from Manteo (MEO) to Spartanburg (SPA)
- Flights from Chicago (ORD) to Greenville (GSP)
- Flights from Fort Lauderdale (FLL) to Greenville (GSP)
- Flights from Montreal (YUL) to Greenville (GSP)
- Flights from Moncton (YQM) to Greenville (GSP)
- Flights to Cross Anchor
- Flights from Halifax (YHZ) to Spartanburg (SPA)
- Flights from Montreal (YUL) to Spartanburg (SPA)
- Flights from Roebuck
- Flights from Calgary (YYC) to Greenville (GSP)
- Flights from Vancouver (YVR) to Greenville (GSP)
- Flights to Lyman
- Flights from Charlotte (CLT) to Greenville (GSP)
- Flights to Woodruff
- Flights from New York (JFK) to Greenville (GSP)
- Flights from Nashville (BNA) to Greenville (GSP)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
